4-Methyl-N-{2-[(E)-3-oxo-3-phenylprop-1-en-1-yl]phenyl}benzenesulfonamide
نویسندگان
چکیده
منابع مشابه
4-Methyl-N-{2-[(E)-3-oxo-3-phenylprop-1-en-1-yl]phenyl}benzenesulfonamide
In the title compound, C22H19NO3S, the terminal phenyl and methyl-phenyl rings are twisted by 37.35 (12) and 49.08 (13)°, respectively, to the central benzene ring. In the crystal, mol-ecules are linked by classical N-H⋯O hydrogen bonds and weak C-H⋯O hydrogen bonds into a three-dimensional supra-molecular network.
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In the title compound, C(21)H(21)N(3)O(2), an intra-molecular N-H⋯O inter-action generates an S(6) ring, which stablizes the enamine-keto tautomer. The S(6) ring makes dihedral angles of 33.07 (7), 56.50 (8) and 38.59 (8)°, respectively, with the benzoyl-acetone benzene ring and the anti-pyrine pyrazole and benzene rings.
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The title compound, C(26)H(24)FNO(3), is a critical inter-mediate of a selective and competitive inhibitor of the enzyme 3-hy-droxy-3-methyl-glutaryl-coenzyme A (HMG-CoA) reductase. Inter-molecular N-H⋯O hydrogen bonding generates a chain along [give direction] that is the dominant inter-action in the crystal packing. Inter-molecular C-H⋯O inter-actions are also observed.
متن کامل(E)-1-(2-Methyl-4-phenylquinolin-3-yl)-3-phenylprop-2-en-1-one
In the title compound, C(25)H(19)NO, the quinoline ring system is approximately planar, with a maximum deviation of 0.32 (1) Å, and forms dihedral angles of 80.74 (3) and 81.71 (4)° with the two phenyl rings. In the crystal. mol-ecules are stacked along the b axis by way of a C-H⋯π inter-action and a weak π-π inter-action between the pyridine and phenyl rings with a centroid-centroid distance o...
متن کاملCrystal structure of the chalcone (E)-3-(furan-2-yl)-1-phenylprop-2-en-1-one
The title chalcone derivative, C13H10O2, adopts an E conformation about the C=C double bond. The mol-ecule is composed of a furanyl and a phenyl ring, bridged by an α,β-unsaturated carbonyl system, which are inclined to one another by 24.07 (7)°. In the crystal, mol-ecules are connected by weak C-H⋯O hydrogen bonds involving the carbonyl O atom acting as a trifurcated acceptor and C-H⋯π inter-a...
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ژورنال
عنوان ژورنال: Acta Crystallographica Section E Structure Reports Online
سال: 2014
ISSN: 1600-5368
DOI: 10.1107/s1600536814015311